Bactrim is a combination of two man-made (man-made) antibiotics, sulfamethoxazole and trimethoprim. Both drugs reduce the capacity of part bacteria to make use of folic mountain for growing. Sulfamethoxazole is one anti-bacterial sulfonamide, a "sulfa" drug. It disrupts the production of dihydrofolic mountain while trimethoprim disrupts the production of tetrahydrofolic acid. Dihydrofolic acid and tetrahydrofolic mountain are forms of folic mountain that bacteria and human cells usage for producing proteins. Trimethoprim inhibits production of tetrahydrofolic acid by inhibiting the enzyme responsible for making tetrahydrofolic acid from dihydrofolic acid. By combine both drugs, two vital steps forced in the manufacturing of bacter proteins are interrupted, and also the combination is much more effective 보다 either drug alone. Bactrim was authorized by the FDA in 1973.




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What brand names are available for sulfamethoxazole and also trimethoprim?


Bactrim, Bactrim DS, Sulfatrim Pediatric


Is sulfamethoxazole and trimethoprim obtainable as a generic drug?


GENERIC AVAILABLE: Yes


Do I need a prescription for sulfamethoxazole and also trimethoprim?


Yes


What are the offers for sulfamethoxazole and trimethoprim?


Sulfamethoxazole/trimethoprim is used for dealing with infections due to susceptible bacteria. Examples incorporate urinary street infections, flares of chromic bronchitis due to bacteria, middle ear infections, for avoidance of infections due to pneumococcus in body organ transplant recipients, for the therapy or prevention of Pneumocystis carinii pneumonia, chancroid, and prevention of toxoplasma encephalitis in patients v AIDS.


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What room the side impacts of sulfamethoxazole and trimethoprim?


Common side impacts of sulfamethoxazole/trimethoprim are: lethargy, various other side impacts include:

low white blood cabinet count,

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What is the dosage for sulfamethoxazole and trimethoprim?


The encourage adult dose because that urinary street infections is one double strength tablet (Bactrim DS, Septra DS) or two solitary strength tablet computers every 12 hrs for 10 to 14 days.

Flares of chronic bronchitis space treated through a comparable regimen because that 14 days.

Sulfamethoxazole/trimethoprim need to be taken through 6 to 8 ounces of liquid to stop crystals from creating in the urine. Persons with progressed kidney an illness may require lower doses.




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Which medicine or supplements interact with sulfamethoxazole and also trimethoprim?


Sulfamethoxazole/trimethoprim can enhance the blood-thinning effects of warfarin (Coumadin), possibly bring about bleeding. Sulfonamides such together sulfamethoxazole deserve to increase the line (break-down and also elimination) the cyclosporine (causing ns of efficiency of cyclosporine), and also can include to the kidney damage caused through cyclosporine.

All sulfonamides deserve to crystallize in urine when the to pee is acidic. Due to the fact that methenamine (Hiprex, Urex, Mandelamine) causes acidic urine, it need to not be provided with sulfonamides.

Blood level of phenytoin (Dilantin) may be increased by treatment v sulfamethoxazole/trimethoprim. This may cause side effects connected with phenytoin (Dilantin, Dilantin-125) such asdizziness, and also reduced attention. Sulfamethoxazole/trimethoprim additionally may rise blood levels of digoxin (Lanoxin) and possibly bring about serious toxic effects. Anemia, as result of a reduction in folic acid, can take place in persons receiving sulfamethoxazole/trimethoprim in mix with:

trimetrexate.

Increased blood levels of potassium may occur when sulfamethoxazole/trimethoprim is an unified with ACE inhibitors.