Medically reviewed by Daniel Murrell, M.D. — written by Jill Seladi-Schulman, Ph.D. — update on September 18, 2018

Overview

The mesentery is a constant set that tissues located in your abdomen. That attaches your intestines to the wall surface of your abdomen and also holds lock in place.

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In the past, the researchers assumed the mesentery was made up of several different structures. However, a 2016 write-up published in The Lancet: Gastroenterology and Hepatology listed enough evidence to classify the mesentery together a single, constant organ.

Keep reading to learn much more about the structure of the mesentery and also what its brand-new classification as a solitary organ method for ab conditions, including Crohn’s disease.


Anatomy and function of the mesentery

Anatomy

The mesentery is found in your abdomen, where it surrounds your intestines. It originates from the area on the back side of her abdomen whereby your aorta branches off to another big artery called the remarkable mesenteric artery. This is periodically referred to as the root an ar of the mesentery. The mesentery fans out from this root an ar to its places throughout your abdomen.


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While the mesentery is a solitary structure, it has several parts:

Small-intestinal mesentery. This region is associated to your little intestine, particularly the jejunum and ileum regions. These space the last two areas of your tiny intestine before it connects come your big intestine.Right mesocolon. This area the the mesentery runs level along your posterior abdominal wall. Think of her posterior abdominal wall as the “back wall” of your body cavity.Transverse mesocolon. This broad an ar of the mesentery connects her transverse colon to your posterior abdominal muscle wall. Your transverse colon is the biggest section that your huge intestine.Left mesocolon. favor the ideal mesocolon, this area the the mesentery likewise runs level along your posterior ab wall.Mesosigmoid. This an ar connects her sigmoid colon to your pelvic wall. Your sigmoid colon is the an ar of her colon just prior to your rectum.Mesorectum. This component of the mesentery is connected to your rectum.

Function

The mesentery attaches her intestines to the wall surface of your abdomen. This keeps your intestines in place, avoiding it indigenous collapsing down into your pelvic area.

If the mesentery doesn’t properly form during fetal development, the intestines deserve to collapse or twist. This than bring about blocked blood ship or tissue fatality in the abdomen, which are both major conditions.

Your mesentery additionally contains lymph nodes. Lymph nodes are little glands the are located throughout your body that help to fight off infections. They contain several species of immune cells and also can trap pathogens, such as viruses and bacteria. Lymph nodes in the mesentery have the right to sample bacteria from her intestines and also generate one immune solution when necessary.

Your mesentery can additionally produce a protein referred to as C-reactive protein (CRP), i m sorry is a authorize of inflammation. That usually developed in your liver, however fat cell in your mesentery can additionally produce it.


This brand-new understanding of the mesentery and how that functions can be a game changer for how doctors understand and also treat details conditions. Crohn’s condition is a an excellent example that this.

Crohn’s an illness is a form of inflammatory bowel disease that causes inflammation of your digestive tract and also bowel tissue. This inflammation deserve to lead to pain, diarrhea, and trouble absorbing nutrients indigenous food.

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The mesentery of world with Crohn’s condition often has boost in the amount and also thickness that fat tissue. Fat cell in the mesentery can produce proteins that are linked with inflammation, consisting of CRP. A 2016 study linked this fat tissue in the mesenteries of human being with Crohn’s disease to enhanced inflammation, CRP production, and bacterial invasion.

This connection argues that targeting the mesentery might be an efficient treatment choice for Crohn’s disease. Because that example, a probiotic treatment was displayed to enhance inflammation-related dysfunction in mesentery tissue samples from world with Crohn’s disease. In addition, removing component of the mesentery might be one effective method to reduce the possibility of Crohn’s disease returning ~ a bowel resection.