In our latest question and answer, our pharmacist discusses whether or not it OK to take Zyrtec (cetirizine) with Mucinex.

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Jay asked

This afternoon roughly 4pm I took a Zyrtec for allergy associated symptoms, 6 hours I took Mucinex rapid max to help with runny nose and sneezing. I discovered out that both have antihistamine in them and I am pertained to around if I took as well much. Both have actually 10mg of antihistamine in them. Should I be worried?


You don"t must be worried. If you took Zyrtec and Mucinex Fast-Max sixhrs acomponent, the worst you are likely to suffer is added drowsiness and also drymouth. Using alcohol or various other drugs through either or both of these medicationswill certainly likely intensify the drowsiness substantially. This may considerably impair yourcapability to drive or usage machinery, so please usage caution and be safe.

Mucinex Fast-Max is a product line in which tbelow are multiple versions intfinished to treat a variety of symptoms. Reviewing the ingredients of all the Fast-Max line ofcommodities, the nighttime varieties contain either diphenhydramine or doxylamineas an antihistamine.

A quick leskid on antihistamines. There are 2 primary households ofantihistamines, let’s call them old-school and also new-institution to make it easier toremember.

Old-institution antihistamines incorporate drugs prefer

Diphenhydramine (Benedryl)Doxylamine(Unisom, NyQuil)Chlorpheniramine(Chlor-Trimeton, Chlor-Tabs)

These drugs block histamine receptors in both thebrain and the remainder of the body; they likewise interact via a number of other receptortypes. This provides them good at relieving allergy symptoms, however likewise gives them afew unpleasant side results, especially sedation/drowsiness, dry mouth, anddry eyes.

See more: What Are The Two Most Reactive Groups In The Periodic Table ?

New-school antihistamines incorporate drugs like:

Cetirizine (Zyrtec)Fexofenadine (Allegra)Loratadine (Claritin)

These drugs, unlike the old-college ones, are designed so that they can’tcross the barrier that protects the brain from harmful chemicals in your blood.The outcome is they have the right to only block histamine receptors discovered in the remainder of yourbody, and not in the brain, and also so they develop allergy relief via much lessdrowsiness and various other side effects.

That sassist, this doesn’t expect they can’tmake you drowsy, and taking them via various other antihistamines, alcohol, or drugsthat influence the central nervous mechanism (bupropion, benzodiazepines likealprazolam or clonazepam, and others) can develop substantial additive effectsthat might impair your ability to make decisions or run a auto.

Again, mixingthese substances have to be avoided if feasible, and if you should, use caution.Thanks for your question!